Description: Developing new algorithms and software to extract the maximum biological knowledge in 3D-EM and X-ray microscopy.
Started in 1989 and headed by Dr. Jose Maria Carazo and Carlos Oscar Sanchez Sorzano, the Biocomputing Unit (BCU) of the National Center for Biotechnology / Instruct Image Processing Center (I2PC) works in the area of cryo electron microscopy.
We develop new ways to extract information from very noisy electron microscopy images obtained under cryogenic conditions, and we integrate these new tools into advanced image processing software packages such as XMIPP and and Scipion , together with integrative biological environments such as 3DBIONOTES.
We, naturally, are the first testing and applying these new tools in projects involving the study of key biomedical systems, such as EGF Receptors in the context of the ERC-Synergy project “HighResCells” or hepatocytes polarization in “TomoXLiver”.