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The supposed ‘gold standard’ method of medical research is the ‘randomised controlled trial’. What this means in drug therapy research is that a group of individuals are randomly assigned to the treatment being studied or placebo, and the outcomes and effects compared. In the ‘best’ trials, neither the study participant not the investigators know who […]

When men middle-aged or elderly men have some difficulty with urination, their doctor’s attention will usually focus on their prostate – the gland that encircles the pipe that takes urine from the bladder to the outside known as the urethra. An enlarged prostate can impinge on the outflow of urine from the bladder and therefore […]

I have written more than once about Professor Sir Rory Collins. He leads the Cholesterol Treatment Trialists collaboration in Oxford, UK. Periodically, this group takes (private) statin study data and churns out bold pronouncements on the (supposed) great effectiveness and safety of these drugs. Professor Collins recently tried to get the BMJ to retract two […]

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