Description: Philip Hansten, Pharm.D. and John Horn, Pharm.D., write books on drug interactions. Both are professors at the University of Washington.
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View sample pages: Warfarin interactions Kinase Inhibitors Cytochrome P450 Table
Drug-Drug Interactions
What are drug-drug interactions? In the broadest sense, a drug interaction occurs whenever one drug affects the pharmacokinetics, pharmacodynamics, efficacy, or toxicity of another drug. The two drugs need not physically interact with each other to produce the effect. When the drug combination results in an undesired effect, the drug interaction becomes an adverse drug interaction. Drug interactions are much more common than adverse drug interactions. Should we be concerned about drug interactions? Drug-d