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Slide The Unmet Medical Need The Unmet Medical Need The Unmet Medical Need Multiple Sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. In Europe only there are, around 500,000 people suffering from this disease, which is often diagnosed in individuals (mostly women) aged 20 to 40. With increasing disability, this incurable disease greatly reduces quality of life for patients and imposes a high burden to the society in terms of cost of therapy and chronic need for care.

Multiple Sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. In Europe only there are, around 500,000 people suffering from this disease, which is often diagnosed in individuals (mostly women) aged 20 to 40. With increasing disability, this incurable disease greatly reduces quality of life for patients and imposes a high burden to the society in terms of cost of therapy and chronic need for care. The introduction of disease-modifying therapies, based on anti-inflammatory

While most therapies act to counter the effector stage of disease (e.g., systemic treatment of inflammation), curative therapies need to target factors that induce and/or maintain disease. Promising in this respect are therapies that target only the detrimental immune response against disease-associated antigen (Ag)s. These approaches are known as Ag-specific therapies. Fast-track the development and validation of an advanced therapeutic medicinal product, based on optimized Vitamin D3 (VitD3)-modified tole

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