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Ivermectin is a pill used to treat parasitic infestations , such as those caused by intestinal parasites in animals, and scabies in humans. Ivermectin is cheap and widely used in regions of the world where parasitic infestations are common. It has few undesirable and side effects. Ivermectin is included in the WHO’s Approximate List of Essential Medicines.
People are prescribed ivermectin only orally. The drug is rapidly absorbed, reaching a maximum concentration in plasma (about 50 mcg / l) 4 hours after taking a dose of 12 mg. It is widely distributed throughout the tissues (the volume of distribution is about 50 liters), but slowly and in a limited amount penetrates into the eye media. The half-life is 28 hours. It is excreted almost exclusively with feces.
Laboratory studies have shown that Ivermectin can slow down the reproduction of the COVID-19 virus (SARS-CoV-2), but such an effect on humans would require large doses. It should only be used in well-planned studies (called randomized controlled trials) evaluating potential effects.