jcponcer.info - The Poncer Lab - Research

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Plasticity in cortical networks & epilepsy

Our team explores the properties of cortical synapses and networks, the mechanisms governing their plasticity and their alteration in the pathology. Our work focuses in particular on GABAergic synapses and networks underlying inhibitory neurotransmission in the adult brain.

Our aim is to understand the molecular mechanisms that regulate the organization, the function and the plasticity of GABAergic synapses and networks. We hope to identify therapeutic targets of interest for disorders involving malfunction of GABA neurotransmission, such as epilepsy and Rett syndrome as well as psychiatric conditions such as bipolar disorders.

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