Description: Fluorescent unnatural amino acids such as L-Anap OMe and L-Anap TFA
molecular imaging (17) fluorescent microscopy (2) 3-6-acetylnaphthalen-2-ylamino (1) l-anap (1) unnatural amino acids (1) aminoacyl-trna synthetase (1) genetically encoded fluorophore (1)
L-Anap allows researchers to fluorescently label any protein with a single amino acid substitution.
AsisChem is the only commercial supplier of L-Anap, which was was first synthesized by Chaterjee et al [1] . We supply two versions of L-ANAP: the first is a trifluoroacetate salt (L-ANAP*TFA), the other is a methyl ester derivative (L-ANAP-OMe), that relies on cellular esterase activity to enter cells non-reversibly.
Our synthesis of L-ANAP-OMe has been verified to work with the same tRNA/synthetase pair that has been used for successful incorporation into proteins in yeast [2] , xenopus oocytes [3] , and multiple mammalian cell types [4] including HEK293 and CHO cells and is available through Addgene .