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Ambrisentan is indicated specifically for the treatment of pulmonary arterial hypertension.Pulmonary hypertension (PAH) is a condition in which there is increased blood pressure in the arteries in lungs. It is used to improve exercise capacity and delay clinical worsening insubjects with symptoms of PAH.
Ambrisentan is supplied in 2 different strengths for oral administration and can be taken with or without food. Swallow tablet as whole and do not split, crush, or chew tablets. The recommended initial dose of the drug is 5 mg once daily. It may be increased to 10 mg once daily if the 5 mg dose is tolerated.