Description: The gastrointestinal (GI) tract is a key hub for maintaining the body’s health. Homeostasis of the GI tract can be influenced by both intrinsic as well as extrinsic factors. Host factors include metabolism, signaling and differentiation of the multiple cell types lining the GI tract, while exogenous factors include luminal microbiota and metabolites, as well as diet.
The gastrointestinal (GI) tract is a key hub for maintaining the body’s health. Homeostasis of the GI tract can be influenced by both intrinsic as well as extrinsic factors. Host factors include metabolism, signaling and differentiation of the multiple cell types lining the GI tract, while exogenous factors include luminal microbiota and metabolites, as well as diet. Understanding the roles of each of these mediators as well as their interplay is critical for developing approaches to disrupt the development
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