Description: NutriEpiGen
The results from our latest study entitled “Tomatoes consumed in-season prevent oxidative stress in Fischer 344 rats: impact of geographical origin”, seems to indicate this. The aim of this study was to evaluate the antioxidant properties of tomatoes consumed in-season from two different geographical origins (local LT or non-local NLT) in Fischer 344 rats.
MicroRNAs (miRNAs) regulate the expression of genes associated with the development of diseases, including type 2 diabetes mellitus (T2DM). However, the use of miRNAs to predict T2DM remission has been poorly studied. Therefore, we aimed to investigate whether circulating miRNAs could be used to predict the probability of T2DM remission in patients with coronary heart disease.
Our study suggests a possible association between epigenetic regulation of inflammatory mediators of visceral adipose tissue (VAT) in the context of colorectal cancer (CRC). This situation could be regulated, in part, by serum 25 (OH) D, as we observed an association between IL6 methylation and CRC risk, through 25 (OH) D. IL6 expression in VAT is a good prognostic factor for CRC, suggesting that IL6 could be an interesting target at HAT levels for CRC prevention.