Description: The Pathogenomics of Innate Immunity, or PI2, project is a Genome Canada-funded project studying the mammalian innate immune system - the body's first line of defense against a range of bacteria, viral and other pathogens. Through the use of microarrays, mouse embryonic stem cell knockouts, siRNA, and bioinformatics, the project's aim is to understand key pathways and decision points in this important biological process.
genomics (286) stem cells (191) pathogens (42) microarrays (12) innate immunity (3) pi2 (2) pathogenomics (1) genome canada (1) genome bc (1) genome prairie (1)
Dr. Robert E.W.Hancock, Professor of Microbiology and Immunology at UBC, and Dr. Lorne Babiuk, Professor of Veterinary Microbiology at the University of Saskatchewan, are leading the PI2 project, which will draw upon many of the unique research findings of a previous Genome Canada project, the Functional Pathogenomics of Mucosal Immunity Program . The PI2 project will advance our understanding of immune responses in humans and animals. Specific genes will be knocked out in mouse embryonic cells and in mice
This project is supported by Genome British Columbia, Genome Prairie and Genome Canada, a not-for-profit organization which is leading Canada's national strategy on genomics with $ 600 million in funding from the federal government.
© 2006 Pathogenomics of Innate Immunity: A GenomeBC Project