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According to recent US Census Data, St. Charles County is home to the four fastest-growing large municipalities in the St. Louis metro area. From 2020 - 2022, Wentzville was the region's growth leader, posting a 6% population increase, followed by O’Fallon, St. Peters, and the City of St. Charles.

The City of O'Fallon also made the top 10 and was again the only city with a population of more than 75,000 to be recognized.

The ranking is based on the net gain of one-way U-Haul® trucks during the past year.