Description: Jan Steyaert pioneered the use of Nanobodies in X-ray crystallography and cryo-EM, aiming at the highest hanging fruits in structural biology including membrane proteins, amyloidogenic proteins, and (transient) multiprotein complexes. Current research is focussing on the engineering of Nanobodies to be used as research tools in biotechnology and molecular pharmacology and on the discovery of Nanobodies that modulate the function of difficult targets to develop first-in-class drugs.
We engineer Nanobodies to be used as research tools in biotechnology and molecular pharmacology.
We discover Nanobodies that modulate the function of difficult targets to develop first-in-class drugs.
Jan Steyaert Science Director Full professor at the Vrije Universiteit Brussel Director of the VIB-VUB center for Structural Biology since 2017 Founder of ConfoTerapeutics , 2015 VIB group leader since 1995 Postdoc at ILRI , Nairobi, Kenya, 1993-1994 PhD work at Plant Genetic Systems and the VUB, Belgium, 1991