The Toxin and Toxin Target Database (T3DB) , or, soon to be referred as, the Toxic Exposome Database , is a unique bioinformatics resource that combines detailed toxin data with comprehensive toxin target information. The database currently houses 3,678 toxins described by 41,602 synonyms, including pollutants, pesticides, drugs, and food toxins, which are linked to 2,073 corresponding toxin target records. Altogether there are 42,374 toxin, toxin target associations. Each toxin record (ToxCard) contains ov
The focus of the T3DB is on providing mechanisms of toxicity and target proteins for each toxin. This dual nature of the T3DB, in which toxin and toxin target records are interactively linked in both directions, makes it unique from existing databases. It is also fully searchable and supports extensive text, sequence, chemical structure, and relational query searches. It is both modelled after and closely linked to the Human Metabolome Database (HMDB) and DrugBank . Potential applications of T3DB include to