VDJtools is an open-source Java/Groovy-based framework designed to facilitate analysis of immune repertoire sequencing ( RepSeq ) data. VDJtools computes a wide set of statistics and is able to perform various forms of cross-sample analysis. Both comprehensive tabular output and publication-ready plots are provided.
For the period of VDJtools development, there were no other software tools able to perform a comprehensive RepSeq post-analysis. Therefore most of the analysis of this kind was done using in-house scripts, which definitely leads to “re-inventing the bicycle” problem and loss of analysis reproducibility.
The main aims of the VDJtools Project are: