Description: T cell Based Immunotherapies for Cancer and Chronic Infectious Diseases
infectious diseases (79) t cell (7) virion (4) cd8+ (2) virion therapeutics (1) viriontx (1) new therapeutic approach (1) treating cancer (1) vron-0200 (1) vron-0100 (1)
T cell-based Immunotherapies for Cancer and Infectious Diseases
The discovery and use of checkpoint inhibitors has revolutionized cancer treatment. But immunotherapies that can optimize CD8 + T cell responses have the potential to further improve clinical outcomes for many infectious diseases and cancers. Our iterative scientific approach is designed to produce novel, adaptable, and accessible disease-specific CD8 + T cell-based immunotherapies.
Our novel immunotherapies have shown promising results in various preclinical models and investigational new drug application (IND)-enabling research activities. Future clinical studies will evaluate our therapeutic approach using our novel VIACT™ platform, which combines genetically encoded checkpoint modifiers with intelligently selected and optimized target antigens, inserted into heterologous chimpanzee adenoviral vectors. Our lead VRON-0200 HBV program is scheduled for our first-in-human study at the e